Article
Tuberculosis bacilli still posing a threat. Polymorphism of genes regulating anti-mycobacterial properties of macrophages.
Polish journal of microbiology - 1 Jan 2006
Druszczyńska Magdalena, Strapagiel Dominik, Kwiatkowska Sylwia, Kowalewicz-Kulbat Magdalena, Rózalska Barbara, Chmiela Magdalena, Rudnicka Wiesława
Abstract excerpt
One third of the earth's population is infected with Mycobacterium tuberculosis, but only 5-10% of the infected individuals will develop active disease over their lifetime. To identify the genes responsible for the variation in the human susceptibility/resistance to tuberculosis (TB) we determined the polymorphisms of three genes crucial for the function of macrophages, in TB patients and healthy controls with no...
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