Article
A Western blot and molecular genetic investigation of the estrogen receptor beta in giant cell arteritis.
Clinical and experimental rheumatology - 1 Jan 2000
Larsson K, Nordborg C, Moslemi A-R, Nordborg E
Abstract excerpt
OBJECTIVE: The epidemiology of giant cell arteritis (GCA) may indicate a pathogenetic relationship between GCA and female sex hormone metabolism; GCA is two to four times more common in women compared with men. Our previous analyses gave no support for the hypothesis that the pathogenesis of GCA should be related to somatic mutations in the estrogen receptor alpha (ERalpha) gene. The object of the present study...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.