Article
Association of apolipoprotein E and B polymorphisms with serum lipids.
Annals of medicine - 1 Dec 1991
Lehtimäki T, Moilanen T, Aalto-Setälä K, Kontula K, Porkka K, Akerblom H K, Ehnholm C, Rönnemaa T, Viikari J
Abstract excerpt
Genetic polymorphism of apolipoprotein E (apoE) and the Xbal restriction-fragment-length polymorphisms (RFLP) of the gene for apolipoprotein B (apoB) have both been shown to be associated with plasma lipid concentration. We studied the combined effect of these gene polymorphisms on serum cholesterol concentrations in 300 subjects aged nine to 18 years. In three way ANOVA, there was a statistically significant...
Topics
- Adolescent
- Analysis of Variance
- Apolipoproteins B
- Apolipoproteins E
- Child
- Cholesterol
- Coronary Disease
- Female
- Finland
- Humans
- Immunoblotting
- Male