Article
Identification of twelve new RFLP-markers on chromosome 22q11-qter.
Human genetics - 1 Dec 1991
Carlbom E, Sugawa N, Larsson C, Scambler P J, Dumanski J P, Collins V P, Nordenskjöld M
Abstract excerpt
We have previously identified and regionally localized 195 chromosome-22-specific DNA markers. We now report restriction fragment length polymorphisms detected by 9 phage markers mapped to 22q11-q12, two cosmid clones mapped to 22q12-q13 and one plasmid mapped to 22q13-qter. These markers may be useful tools for mapping disease genes such as the NF2 locus, on chromosome 22.
Topics
- Alleles
- Blotting, Southern
- Chromosomes, Human, Pair 22
- Cloning, Molecular
- Cosmids
- DNA Restriction Enzymes
- Genetic Markers
- Humans
- Polymorphism, Restriction Fragment Length