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Article

Identification of target genes of the homeotic gene Antennapedia by enhancer detection.

Genes & development - 1 Dec 1991

Wagner-Bernholz J T, Wilson C, Gibson G, Schuh R, Gehring W J

Abstract excerpt

Localized expression of the homeotic gene Antennapedia (Antp) in Drosophila melanogaster is required for normal development of the thoracic segments. When the Antp gene is expressed ectopically in the larval primordium of the antenna, the antennal imaginal disc, the developmental fate of the disc is switched and the adult antenna is transformed to a mesothoracic leg. We screened approximately 550 different fly...

Topics

Alleles
Animals
Drosophila melanogaster
Enhancer Elements, Genetic
Extremities
Gene Expression Regulation
Genes, Homeobox
Genes, Regulator
Species Specificity
Thorax
Transcriptional Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 1684334
DOI: 10.1101/gad.5.12b.2467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1684334-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Identification of target genes of the homeotic gene Antennapedia by enhancer detection.PMID 1684334Read ↗

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