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Article

Cortical inhibition modified by embryonic neural precursors grafted into the postnatal brain.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 12 Jul 2006

Alvarez-Dolado Manuel, Calcagnotto Maria Elisa, Karkar Kameel M, Southwell Derek G, Jones-Davis Dorothy M, Estrada Rosanne C, Rubenstein John L R, Alvarez-Buylla Arturo, Baraban Scott C

Abstract excerpt

Embryonic medial ganglionic eminence (MGE) cells transplanted into the adult brain can disperse, migrate, and differentiate to neurons expressing GABA, the primary inhibitory neurotransmitter. It has been hypothesized that grafted MGE precursors could have important therapeutic applications increasing local inhibition, but there is no evidence that MGE cells can modify neural circuits when grafted into the...

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Identifiers

PMID: 16837585
DOI: 10.1523/JNEUROSCI.1540-06.2006
PMCID: PMC1550786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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