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Article

Genetic characterisation of circulating fetal cells allows non-invasive prenatal diagnosis of cystic fibrosis.

Prenatal diagnosis - 1 Oct 2006

Saker Ali, Benachi Alexandra, Bonnefont Jean Paul, Munnich Arnold, Dumez Yves, Lacour Bernard, Paterlini-Brechot Patrizia

Abstract excerpt

OBJECTIVES: Cystic fibrosis (CF) is an autosomal recessive disease due to mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The purpose of this study was to develop a molecular method to characterise both paternal and maternal CFTR alleles in DNA from circulating fetal cells (CFCs) isolated by ISET (isolation by size of epithelial tumour/trophoblastic cells). METHODS: The molecular...

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Source

Identifiers

PMID: 16832834
DOI: 10.1002/pd.1524

Genes

CFTR
ADO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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