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Article

Localization of the Rho GTPases and some Rho effector proteins in the sperm of several mammalian species

6 Jul 2006

Abstract excerpt

The acrosome reaction is a fundamental event in the biology of the sperm and is a prerequisite to fertilization of the egg. Members of the Rho family of GTPases and their effectors are present in the cytoplasm and/or plasma membrane overlying the acrosome of porcine sperm. We have implicated the Rho family of GTPases and the Rho-activated kinase, ROCK-1, in mediating the zona-pellucida-induced acrosome reaction....

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PMID: 16822336
DOI: 10.1017/s0967199406003790

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