Article
An immunohistochemical study of P53 and Ki-67 in gastrointestinal adenoma and adenocarcinoma using tissue microarray.
Anticancer research - 1 Jan 2000
Zheng Huachuan, Tsuneyama Koichi, Cheng Chunmei, Takahashi Hiroyuki, Cui Zhengguo, Murai Yoshihiro, Nomoto Kazuhiro, Takano Yasuo
Abstract excerpt
BACKGROUND: Gastrointestinal carcinogenesis generally follows the adenoma-adenocarcinoma sequence and tumor metastasis determines the survival time of the patients. The expressions of p53 and ki-67 in gastrointestinal adenoma and adenocarcinoma (GIA) were explored and their clinicopathological significance determined. MATERIALS AND METHODS: The expressions of mutant p53 and ki-67 were examined on tissue...
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