Article
Epidermal growth factor receptor mutations and response to chemotherapy in patients with non-small-cell lung cancer.
Japanese journal of clinical oncology - 1 Jun 2006
Lee Kyung-Hun, Han Sae-Won, Hwang Pil Gyu, Oh Do-Youn, Kim Dong-Wan, Chung Doo Hyun, Im Seock-Ah, Kim Tae-You, Heo Dae Seog, Bang Yung-Jue
Abstract excerpt
BACKGROUND: The association of epidermal growth factor receptor (EGFR) mutations with the response to conventional cytotoxic chemotherapeutic agents in non-small-cell lung cancer patients has not been investigated. We retrospectively analyzed the associations between response to chemotherapy and molecular markers associated with gefitinib responsiveness including EGFR mutations. METHODS: EGFR (exons 18, 19 and...
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