Article
Cerebral amyloid angiopathy and cortical microinfarcts as putative substrates of vascular dementia.
International journal of geriatric psychiatry - 1 Jul 2006
Haglund Mattias, Passant Ulla, Sjöbeck Martin, Ghebremedhin Estifanos, Englund Elisabet
Abstract excerpt
BACKGROUND AND PURPOSE: Vascular dementia (VaD) has occasionally been associated with cerebral amyloid angiopathy (CAA), but the prevalence and significance of this counterintuitive relationship are poorly known. Therefore, we investigated the presence and characteristics of CAA in brains of VaD cases. METHODS: We examined temporal and parietal regions of the cerebral cortex of 26 consecutive VaD cases from the...
Topics
- Aged, 80 and over
- Apolipoproteins E
- Cerebral Amyloid Angiopathy
- Cerebral Infarction
- Cerebrovascular Circulation
- Dementia, Vascular
- Female
- Follow-Up Studies
- Genotype
- Humans
- Male
- Parietal Lobe
- Phenotype
- Retrospective Studies
- Severity of Illness Index
- Temporal Lobe
