Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mesodermal Wnt2b signalling positively regulates liver specification.

Nature - 10 Aug 2006

Ober Elke A, Verkade Heather, Field Holly A, Stainier Didier Y R

Abstract excerpt

Endodermal organs such as the lung, liver and pancreas emerge at precise locations along the primitive gut tube. Although several signalling pathways have been implicated in liver formation, so far no single gene has been identified that exclusively regulates liver specification. In zebrafish, the onset of liver specification is marked by the localized endodermal expression of hhex and prox1 at 22 hours post...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Transplantation
Share to Animals, Genetically Modified
Share to beta Catenin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Glycoproteins

Share to Hepatocytes

Share to Mesoderm

Share to Wnt Proteins

Share to Zebrafish Proteins

Source

Identifiers

PMID: 16799568
DOI: 10.1038/nature04888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mesodermal Wnt2b signalling positively regulates liver specification.PMID 16799568Read ↗

Primitive Hepatoblasts Driving Early Liver DevelopmentSemantic proximity Read ↗

Molecular mechanisms of liver and bile duct developmentSemantic proximity Read ↗

Zebrafish hhex regulates liver development and digestive organ chirality.Semantic proximity Read ↗

New school in liver development: Lessons from zebrafish #Semantic proximity Read ↗

Organ-specific requirements for Hdac1 in liver and pancreas formation.Semantic proximity Read ↗

Notch signaling controls liver development by regulating biliary differentiationSemantic proximity Read ↗

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitmentSemantic proximity Read ↗

Development of the Intrahepatic and Extrahepatic Biliary Tract: A Framework for Understanding Congenital DiseasesSemantic proximity Read ↗

Cell lineage specification during development of the anterior lateral plate mesoderm and forelimb fieldSemantic proximity Read ↗

Reiterative use of the notch signal during zebrafish intrahepatic biliary developmentSemantic proximity Read ↗

Embryonic development of the liver†Semantic proximity Read ↗

Rargb regulates organ laterality in a zebrafish model of right atrial isomerism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.