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Article

Detection of thebcl-2t(14;18) Translocation and Proto-Oncogene Expression in Primary Intraocular Lymphoma

23 Jun 2006

Abstract excerpt

PURPOSE: Primary intraocular lymphoma (PIOL) is a diffuse large B cell lymphoma that initially infiltrates the retina, vitreous, or optic nerve head, with or without central nervous system involvement. This study examined the expression of the bcl-2 t(14;18) translocation, the bcl-10 gene, and high expression of bcl-6 mRNA in PIOL cells. METHODS: Microdissection and PCR analysis were used to examine vitreous...

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PMID: 16799010
DOI: 10.1167/iovs.05-1312

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