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Article

Identification of Common Transcriptional Regulatory Elements in Interleukin-17 Target Genes

23 Jun 2006

Abstract excerpt

Interleukin (IL)-17 is the founding member of a novel family of inflammatory cytokines. Although produced by T cells, IL-17 activates genes and signals typical of innate immune mediators such as tumor necrosis factor (TNF)-alpha and IL-1beta. Most IL-17 target genes characterized to date are cytokines or neutrophil-attractive chemokines. Our recent microarray studies identified an acute phase response gene,...

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PMID: 16798734
DOI: 10.1074/jbc.m604597200

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