Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient.

doi:10.1016/0167-4781(91)90035-k

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Article

Characterization of the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase (ACAA). No large DNA rearrangement in a thiolase-deficient patient.

Biochimica et biophysica acta - 27 Aug 1991

Bout A, Franse M M, Collins J, Blonden L, Tager J M, Benne R

Abstract excerpt

We have characterized the gene encoding human peroxisomal 3-oxoacyl-CoA thiolase, an enzyme operative in the peroxisomal beta-oxidation system. We found one version of this gene (gene symbol ACAA) in the human genome, in contrast to the situation in rat where two versions have been described. The...

Topics

Acetyl Coenzyme A
Acetyl-CoA C-Acetyltransferase
Amino Acid Sequence
Animals
Base Sequence
Blotting, Northern
Blotting, Southern
DNA, Single-Stranded
Exons
Humans
Introns
Microbodies
Molecular Sequence Data
Mutation
Promoter Regions, Genetic
Rats

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Identifiers

PMID: 1679347
DOI: 10.1016/0167-4781(91)90035-k

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1679347-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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