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Article

Novelty seeking as a moderator of familial risk for alcohol dependence.

Alcoholism, clinical and experimental research - 1 Jul 2006

Grucza Richard A, Robert Cloninger C, Bucholz Kathleen K, Constantino John N, Schuckit Marc I, Dick Danielle M, Bierut Laura J

Abstract excerpt

BACKGROUND: Disinhibitory personality traits such as high novelty seeking (NS) are moderately heritable, and individuals with substance use disorders (SUDs) frequently exhibit such traits. However, recent studies have cast doubt on the supposition that such traits are true familial risk factors for SUD and particularly for alcohol dependence. Another possibility is that familial risk interacts with...

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PMID: 16792565
DOI: 10.1111/j.1530-0277.2006.00133.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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