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Article

Developmental and functional evidence of nuclear immaturity in prepubertal oocytes

3 Jun 2006

Abstract excerpt

BACKGROUND: The nuclear compartment has been proposed as responsible for the developmental arrest of prepubertal mouse oocytes while the studies on prepubertal sheep and cow oocyte model suggested the cytoplasm immaturity accounts for this failure. METHODS: The apparent disagreement on the causes of developmental defects between these two species prompted us to study: (i) follicular and oocyte growth allometry in...

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PMID: 16790612
DOI: 10.1093/humrep/del184

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