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Article

Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents.

Journal of medicinal chemistry - 29 Jun 2006

Lin Li, Shi Qian, Nyarko Alexander K, Bastow Kenneth F, Wu Chin-Chung, Su Ching-Yuan, Shih Charles C-Y, Lee Kuo-Hsiung

Abstract excerpt

In a continuing study of curcumin analogues as potential drug candidates to treat prostate cancer at both androgen-dependent and androgen-refractory stages, we designed and synthesized over 40 new analogues classified into four series: monophenyl analogues (series A), heterocycle-containing analogues (series B), analogues bearing various substituents on the phenyl rings (series C), and analogues with various...

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Source

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Identifiers

PMID: 16789753
DOI: 10.1021/jm051043z
PMCID: PMC2597393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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