Article
Familial dilated cardiomyopathy with troponin T K210del mutation.
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology - 1 Mar 2006
Martins Elisabete, Silva-Cardoso J, Alves Cíntia, Pereira Helena, Soares Benilde, Damasceno Albertino, Abreu-Lima Cassiano, Amorim António, Rocha-Gonçalves F
Abstract excerpt
BACKGROUND: It has been estimated that more than 30% of patients with idiopathic dilated cardiomyopathy have a familial form of the disease. The most frequent pattern of inheritance is autosomal dominant and several genes or loci have been implicated, coding for sarcomeric or cytoskeleton proteins. Most of the genotype-phenotype correlations are still under study, but a particular mutation, K210del in the...
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