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Article

Alpha-sarcoglycan is recycled from the plasma membrane in the absence of sarcoglycan complex assembly.

Traffic (Copenhagen, Denmark) - 1 Jul 2006

Draviam Romesh A, Wang Bing, Shand Stuart H, Xiao Xiao, Watkins Simon C

Abstract excerpt

The sarcoglycan complex consists of four subunits in skeletal muscle (alpha, beta, gamma, and delta-SG). Mutations in alpha-sarcoglycan (alpha-SG) result in the most common form of limb girdle muscular dystrophy. However, the function of alpha-SG remains unknown. In this report we attempt to clarify its function by delineating the trafficking pathway of alpha-SG in live cells. We present evidence, utilizing total...

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Identifiers

PMID: 16787395
DOI: 10.1111/j.1600-0854.2006.00433.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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