Altered Cellular Distribution and Subcellular Sorting of γ-Tubulin in Diffuse Astrocytic Gliomas and Human Glioblastoma Cell Lines

doi:10.1097/01.jnen.0000229235.20995.6e

Article

Altered Cellular Distribution and Subcellular Sorting of γ-Tubulin in Diffuse Astrocytic Gliomas and Human Glioblastoma Cell Lines

1 May 2006

Abstract excerpt

Centrosome amplification is a pivotal mechanism underlying tumorigenesis but its role in gliomas is underinvestigated. The present study specifically examines the expression and distribution of the centrosome-associated cytoskeletal protein gamma-tubulin in 56 primary diffuse astrocytic gliomas (grades II-IV) and in 4 human glioblastoma cell lines (U87MG, U118MG, U138MG, and T98G). Monoclonal anti-peptide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest

Altered Cellular Distribution and Subcellular Sorting of γ-Tubulin in Diffuse Astrocytic Gliomas and Human Glioblastoma Cell LinesPMID 16772870Read

Differential expression and cellular distribution of γ‐tubulin and βIII‐tubulin in medulloblastomas and human medulloblastoma cell linesSemantic proximity Read

Post-Translational Tubulin Modifications in Differentiated Human Neural Stem CellsSemantic proximity Read

Class III β-Tubulin Is a Component of the Mitotic Spindle in Multiple Cell TypesSemantic proximity Read

Adult-type and Pediatric-type Diffuse Gliomas : What the Neuroradiologist Should Know.Semantic proximity Read

Pediatric Glial Tumors.Semantic proximity Read

Molecular Pathology of Gliomas.Semantic proximity Read

Primary brain tumours in adults.Semantic proximity Read