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Article

Usefulness of real time PCR for the differentiation and quantification of 652 and JP2 Actinobacillus actinomycetemcomitans genotypes in dental plaque and saliva.

BMC infectious diseases - 13 Jun 2006

Orrù Germano, Marini Mario Francesco, Ciusa Maria Laura, Isola Daniela, Cotti Marina, Baldoni Marco, Piras Vincenzo, Pisano Elisabetta, Montaldo Caterina

Abstract excerpt

BACKGROUND: The aim of our study is to describe a fast molecular method, able to distinguish and quantize the two different genotypes (652 and JP2) of an important periodontal pathogen: Actinobacillus actinomycetemcomitans. The two genotypes show differences in the expression of an important pathogenic factor: the leukotoxin (ltx). In order to evidence this, we performed a real time PCR procedure on the ltx...

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Identifiers

PMID: 16772039
DOI: 10.1186/1471-2334-6-98
PMCID: PMC1539009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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