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Article

The role of single N-glycans in proteolytic processing and cell surface transport of the Lassa virus glycoprotein GP-C.

Virology journal - 31 May 2006

Eichler Robert, Lenz Oliver, Garten Wolfgang, Strecker Thomas

Abstract excerpt

Lassa virus glycoprotein is synthesised as a precursor (preGP-C) into the lumen of the endoplasmic reticulum. After cotranslational cleavage of the signal peptide, the immature GP-C is posttranslationally processed into the N-terminal subunit GP-1 and the C-terminal subunit GP-2 by the host cell subtilase SKI-1/S1P. The glycoprotein precursor contains eleven potential N-glycosylation sites. In this report, we...

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Identifiers

PMID: 16737539
DOI: 10.1186/1743-422X-3-41
PMCID: PMC1524727

Genes

SKI

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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