Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus.

doi:10.1016/0140-6736(91)91705-y

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Article

Clustering of features of von Hippel-Lindau syndrome: evidence for a complex genetic locus.

Lancet (London, England) - 4 May 1991

Neumann H P, Wiestler O D

Abstract excerpt

von Hippel-Lindau syndrome (HLS), an autosomal-dominant inherited disease, was studied in 92 affected subjects from 29 kindreds. In an initial survey to identify HLS gene carriers, all patients treated at the University of Freiburg for angiomatosis retinae (22), haemangioblastoma of the central n...

Topics

Adolescent
Adult
Aged
Aged, 80 and over
Child
Child, Preschool
Chromosome Aberrations
Chromosome Disorders
Chromosome Mapping
Chromosomes, Human, Pair 3
Female
Germany, West
Humans
Male
Middle Aged
Mutation
Prevalence
Space-Time Clustering

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