Article
[Glibenclamide instead of insulin: a new chance for MODY 3 type diabetes patients: case report].
Vnitrni lekarstvi - 1 Mar 2006
Brunerová L, Treslová L, Průhová S, Vosáhlo J, Broz J, Lebl J, Andel M
Abstract excerpt
MODY 3 belongs to monogenic forms of diabetes mellitus and is caused by monoallelic mutation in gene for transcription factor HNF-1alpha, essential for regulation of beta-cell function. Clinical presentation of MODY 3 is similar to that of type 1 diabetes. Although MODY 3 patients are not threatened by ketoacidosis, tight metabolic control is important for prevention of chronic diabetic complications. In the...
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