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Article

Recurrence of proteinuria 10 years post-transplant in NPHS2-associated focal segmental glomerulosclerosis after conversion from cyclosporin A to sirolimus.

Pediatric nephrology (Berlin, Germany) - 1 Oct 2006

Höcker Britta, Knüppel Tanja, Waldherr Rüdiger, Schaefer Franz, Weber Stefanie, Tönshoff Burkhard

Abstract excerpt

Mutations in the NPHS2 gene, which encodes podocin, are associated with steroid-resistant nephrotic syndrome in childhood. Renal histology frequently presents focal segmental glomerulosclerosis (FSGS). Post-transplant recurrence of proteinuria in patients affected by homozygous or compound heterozygous NPHS2 mutation is encountered rarely (1-2%) compared to 30% recurrence in nonhereditary FSGS. We report on a...

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Source

Identifiers

PMID: 16721582
DOI: 10.1007/s00467-006-0148-9

Genes

NPHS2
SRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Recurrence of proteinuria 10 years post-transplant in NPHS2-associated focal segmental glomerulosclerosis after conversion from cyclosporin A to sirolimus.PMID 16721582Read ↗

NPHS2 mutation associated with recurrence of proteinuria after transplantation.Semantic proximity Read ↗

Recurrence of focal segmental glomerulosclerosis after renal transplantation in patients with mutations of podocin.Semantic proximity Read ↗

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Recurrence of focal segmental glomerulosclerosis after kidney transplantation: strategies and outcome.Semantic proximity Read ↗

Podocin-related mechanisms in posttransplant [corrected] recurrence of focal segmental glomerulosclerosis [corrected].Semantic proximity Read ↗

Clinical features and mutational survey of NPHS2 (podocin) in Japanese children with focal segmental glomerulosclerosis who underwent renal transplantation.Semantic proximity Read ↗

FSGS Recurrence in Adults after Renal Transplantation.Semantic proximity Read ↗

Screening for NPHS2 mutations may help predict FSGS recurrence after transplantation.Semantic proximity Read ↗

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