Article
Recurrence of focal segmental glomerulosclerosis after renal transplantation in patients with mutations of podocin.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Jun 2003
Bertelli Roberta, Ginevri Fabrizio, Caridi Gianluca, Dagnino Monica, Sandrini Silvio, Di Duca Marco, Emma Francesco, Sanna-Cherchi Simone, Scolari Francesco, Neri Tauro Maria, Murer Luisa, Massella Laura, Basile Giancarlo, Rizzoni Gianfranco, Perfumo Francesco, Ghiggeri Gian Marco
Abstract excerpt
BACKGROUND: Posttransplant recurrence of focal segmental glomerulosclerosis (FSGS) occurs in a relevant proportion of FSGS patients and represents an important clinical emergency. It is taken as a proof of the existence of circulating permeability plasma factor(s) that are also putative effectors of original proteinuria in these patients. Familial forms of FSGS do not recur, but the discovery of numerous patients...
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