Group A streptococcal infections in injection drug users in Barcelona, Spain: epidemiologic, clinical, and microbiologic analysis of 3 clusters of cases from 2000 to 2003.

doi:10.1097/01.md.0000224707.24392.52

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Group A streptococcal infections in injection drug users in Barcelona, Spain: epidemiologic, clinical, and microbiologic analysis of 3 clusters of cases from 2000 to 2003.

Medicine - 1 May 2006

Sierra Josep M, Sánchez Francesca, Castro Pedro, Salvadó Margarita, de la Red Gloria, Libois Agnes, Almela Manuel, March Francesca, Español Montserrat, Sambeat Maria Antonia, Romeu Joan, Brugal Maria Teresa, de Olalla Patricia García, Gatell Jose Maria, Vila Jordi, García Felipe, Colomés Jose Luís López, Caylà Joan A, Coll Pere

Abstract excerpt

An unexplained resurgence of Group A streptococci (GAS) infections has been observed since the mid-1980s in the United States and Europe, particularly among intravenous drug users (IDUs). Several risk factors have been identified. Mutations in the capsule synthesis regulator genes (csrRS) have been associated with an increase in virulence. From January 1998 to December 2003, we conducted a prospective and...

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PMID: 16721256
DOI: 10.1097/01.md.0000224707.24392.52

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