Article
In vivo contribution of amino acid sulfur to cartilage proteoglycan sulfation.
The Biochemical journal - 15 Sept 2006
Pecora Fabio, Gualeni Benedetta, Forlino Antonella, Superti-Furga Andrea, Tenni Ruggero, Cetta Giuseppe, Rossi Antonio
Abstract excerpt
Cytoplasmic sulfate for sulfation reactions may be derived either from extracellular fluids or from catabolism of sulfur-containing amino acids and other thiols. In vitro studies have pointed out the potential relevance of sulfur-containing amino acids as sources for sulfation when extracellular sulfate concentration is low or when its transport is impaired such as in DTDST [DTD (diastrophic dysplasia) sulfate...
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