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Article

Rescue of F508del CFTR: Commentary on "F508del CFTR with two altered RXR motifs escapes from ER quality control but its channel activity is thermally sensitive".

Biochimica et biophysica acta - 1 May 2006

Tümmler Burkhard

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Topics

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Share to Amino Acid Motifs
Share to Chloride Channels
Share to Cricetinae
Share to Cystic Fibrosis Transmembrane Conductance Regulator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16712779
DOI: 10.1016/j.bbamem.2006.03.033

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rescue of F508del CFTR: Commentary on "F508del CFTR with two altered RXR motifs escapes from ER quality control but its channel activity is thermally sensitive".PMID 16712779Read ↗

F508del CFTR with two altered RXR motifs escapes from ER quality control but its channel activity is thermally sensitive.Semantic proximity Read ↗

Correcting mutant CFTR with a stabilizing nanobody reveals a novel active conformation of the channelSemantic proximity Read ↗

Integrative genomic meta-analysis reveals novel molecular insights into cystic fibrosis and ΔF508-CFTR rescue.Semantic proximity Read ↗

Mechanism of CFTR correction by type I folding correctorsSemantic proximity Read ↗

Manipulating the folding pathway of delta F508 CFTR using chemical chaperones.Semantic proximity Read ↗

Correcting mutant CFTR with a stabilizing nanobody reveals a novel active conformation of the channelSemantic proximity Read ↗

Thermally unstable gating of the most common cystic fibrosis mutant channel (ΔF508): "rescue" by suppressor mutations in nucleotide binding domain 1 and by constitutive mutations in the cytosolic loops.Semantic proximity Read ↗

Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editingSemantic proximity Read ↗

<i>In silico</i> and functional characterisation of an ultra-rare <i>CFTR</i> mutation identifies novel lasso motif interactions regulating channel gatingSemantic proximity Read ↗

Combination of Correctors Rescue ΔF508-CFTR by Reducing Its Association with Hsp40 and Hsp27.Semantic proximity Read ↗

Corrector-mediated rescue of misprocessed CFTR mutants can be reduced by the P-glycoprotein drug pump.Semantic proximity Read ↗

Adenine base editing of CFTR using receptor targeted nanoparticles restores function to G542X cystic fibrosis airway epithelial cellsSemantic proximity Read ↗

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