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Biochemical Aspects of Coronavirus Replication and Virus-Host Interaction

7 Jul 2006

Abstract excerpt

Infection by different coronaviruses (CoVs) causes alterations in the transcriptional and translational patterns, cell cycle, cytoskeleton, and apoptosis pathways of the host cells. In addition, CoV infection may cause inflammation, alter immune and stress responses, and modify the coagulation pathways. The balance between the up- and downregulated genes could explain the pathogenesis caused by these viruses. We...

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PMID: 16712436
DOI: 10.1146/annurev.micro.60.080805.142157

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