Article
Isolation of mutations synthetic-lethal to prohibitin 2 null mutants of Saccharomyces cerevisiae.
Antonie van Leeuwenhoek - 1 Feb 2006
Liu Feng, Jamieson Derek J
Abstract excerpt
Prohibitins are ubiquitous, abundant proteins found in a wide range of organisms and that have a high degree of sequence conservation. In yeast it has previously been demonstrated that prohibitin proteins form a complex and are involved in maintaining the morphological and functional integrity of mitochondria. We have used a colony-sectoring assay as a screen for mutants that are dependent upon the presence of...
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