Article
[The influence of IL-6 polymorphism on efficacy of treatment of rheumatoid arthritis patients with methotrexate and prednisone].
Polskie Archiwum Medycyny Wewnetrznej - 1 Sept 2005
Pawlik Andrzej, Czerny Bogusław, Dabrowska-Zamojcin Ewa, Górnik Wanda, Poziomkowska Iwona, Gawrońska-Szklarz Barbara, Herczyńska Magdalena
Abstract excerpt
Rheumatoid arthritis (RA) is a chronic inflammatory disease in which cytokines play an important role. The therapy of RA is associated with application of the drugs modulating the immune response via inhibiting the cytokine production. The common drugs used in RA therapy are methotrexate and prednisone. Recent investigations showed the importance of genetically determined differences in cytokine production in RA...
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