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Article

Keratoepithelin Suppresses the Progression of Experimental Human Neuroblastomas

15 May 2006

Abstract excerpt

Neuroblastoma is the most common extracranial childhood tumor. High expression of activin A is associated with a favorable prognosis, but the contributing mechanisms have remained unclear. Our previous demonstration of the activin A-mediated up-regulation of keratoepithelin led to the consideration that keratoepithelin could modulate neuroblastoma growth and/or progression. We report here that enhanced...

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PMID: 16707457
DOI: 10.1158/0008-5472.can-05-3049

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