Article
Structural elucidation of the PDI-related chaperone Wind with the help of mutants.
Acta crystallographica. Section D, Biological crystallography - 1 Jun 2006
Sevvana Madhumati, Biadene Marianna, Ma Qingjun, Guo Chaoshe, Söling Hans Dieter, Sheldrick George M, Ferrari David M
Abstract excerpt
The structures of the PDI-related protein Wind (with a C-terminal His(6) tag) and the mutants Y53S, Y53F and Y55K have been determined and compared with the wild-type structure with the His(6) tag at the N-terminus. All five structures show the same mode of dimerization, showing that this was not an artefact introduced by the nearby N-terminal His(6) tag and suggesting that this dimer may also be the biologically...
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