Article
Stratification of medulloblastoma on the basis of histopathological grading.
Acta neuropathologica - 1 Jul 2006
Giangaspero Felice, Wellek Stefan, Masuoka Jun, Gessi Marco, Kleihues Paul, Ohgaki Hiroko
Abstract excerpt
Medulloblastoma (WHO grade IV) is an embryonal tumour of the cerebellum and the most common malignant central nervous system tumour in children. Despite significant advances in treatment, 5-year survival rates are still less than 70%, suggesting the presence of subgroups with different response to radio/chemotherapy. In the present study, we re-evaluated a series of 347 medulloblastomas from the SIOP II clinical...
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