Article
Ethnicity and lipoprotein(a) polymorphism in Native Mexican populations.
Annals of human biology - 1 Jan 2000
Cardoso-Saldaña G, De La Peña-Díaz A, Zamora-González J, Gomez-Ortega R, Posadas-Romero C, Izaguirre-Avila R, Malvido-Miranda E, Morales-Anduaga M E, Anglés-Cano E
Abstract excerpt
BACKGROUND: Lp(a) is a lipoparticle of unknown function mainly present in primates and humans. It consists of a low-density lipoprotein and apo(a), a polymorphic glycoprotein. Apo(a) shares sequence homology and fibrin binding with plasminogen, inhibiting its fibrinolytic properties. Lp(a) is considered a link between atherosclerosis and thrombosis. Marked inter-ethnic differences in Lp(a) concentration related...
Topics
- Ethnicity
- Female
- Fibrin
- Genetic Markers
- Genetics, Population
- Humans
- Indians, North American
- Lipoprotein(a)
- Male
- Mexico
- Phenotype
- Polymorphism, Genetic
- Protein Isoforms
