Article
Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica.
Eukaryotic cell - 1 May 2006
Weber Christian, Guigon Ghislaine, Bouchier Christiane, Frangeul Lionel, Moreira Sandrine, Sismeiro Odile, Gouyette Catherine, Mirelman David, Coppee Jean Yves, Guillén Nancy
Abstract excerpt
Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin.
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