A diffusion approach to approximating preservation probabilities for gene duplicates.

Abstract excerpt

Consider a haploid population and, within its genome, a gene whose presence is vital for the survival of any individual. Each copy of this gene is subject to mutations which destroy its function. Suppose one member of the population somehow acquires a duplicate copy of the gene, where the duplicate is fully linked to the original gene's locus. Preservation is said to occur if eventually the entire population...

Topics

• Algorithms
• Alleles
• Animals
• Computer Simulation
• Gene Duplication
• Genetics, Population
• Haploidy
• Markov Chains
• Models, Genetic
• Models, Statistical
• Mutation
• Probability