Article
Characterization of Cq3, a quantitative trait locus that controls plasma cholesterol and phospholipid levels in mice.
The Journal of veterinary medical science - 1 Apr 2006
Suto Jun-ichi
Abstract excerpt
Cq3 was identified in C57BL/6J (B6) x KK-Ay F2 mice as a quantitative trait locus (QTL) that controls plasma cholesterol and phospholipid levels, and normolipidemic B6 allele was associated with increased lipids. Cq3 was statistically significant in F2-a/a, but not in F2-Ay/a; probably because the Cq3 effect was obscured by introduction of the Ay allele, which in itself has a strong hyperlipidemic effect. Because...
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