Article
FANCD2 associated with sporadic breast cancer risk.
Carcinogenesis - 1 Sept 2006
Barroso E, Milne R L, Fernández L P, Zamora P, Arias J I, Benítez J, Ribas G
Abstract excerpt
Several components of the Fanconi anaemia (FA) family of proteins allow the formation of the DNA repair complex foci formed by proteins such as BRCA1/2 and RAD51. Because the genes that participate in the DNA repair pathway have been described as low-penetrance breast cancer susceptibility genes, we postulated that variants in FA genes could also be associated with sporadic breast cancer risk. We studied seven...
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