Article
Mouth cell collection device for newborn mice.
Molecular genetics and metabolism - 1 Jan 2000
Zhang Y-H, Huang B-L, Eastman K, McCabe L L, MacLennan N K, McCabe E R B
Abstract excerpt
For efficient and accurate genotyping of transgenic and knockout mice, the ability to reduce pain and suffering and to obtain DNA early in life are critical. We have developed a novel method to sample buccal cells from neonatal mice to obtain DNA. Our mouse mouth cell collection process includes an oral speculum and collection device which enables rapid extraction of enough DNA for up to 50 PCRs from each buccal...
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