Article
[Study on matrix metalloproteinase 1, 9, 12 polymorphisms and susceptibility to chronic obstructive pulmonary disease among Han nationality in northern China].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Nov 2005
Zhang Rong-bao, He Quan-ying, Yang Rui-hong, Lu Bing-bing, Liu Yu-jing
Abstract excerpt
OBJECTIVE: To study the association between the functional polymorphism of matrix metalloproteinases (MMPs) and the development of chronic obstructive pulmonary disease (COPD). METHODS: 147 COPD patients and 120 healthy smoking controls were selected. Spirometry and chest X-rays had been taken. Questionnaires including sex, age, smoking history, occupational exposure were completed. MMP-9 (-1562 C/T), MMP-1(-1607...
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