Article
Early in vivo and in vitro effects of amelogenin gene splice products on pulp cells.
European journal of oral sciences - 1 May 2006
Lacerda-Pinheiro Sally, Jegat Nadege, Septier Dominique, Priam Fabienne, Bonnefoix Mireille, Bitard Juliette, Kellermann Odile, Tompkins Kevin, Veis Arthur, Goldberg Michel, Poliard Anne
Abstract excerpt
Recombinant amelogenin gene splice products A+4 and A-4, implanted in the pulp, induce the recruitment, proliferation, and differentiation of reparative cells. Our aim was to investigate the precocious events occurring in the pulp 1 d and 3 d after implantation of agarose beads alone or loaded with A+4 or A-4. Proliferation and cell recruitment towards an odonto/osteogenic phenotype were visualized by detection...
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