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Article

Prognostic relevance of the FAB morphological criteria in chronic lymphocytic leukemia: correlations with IgVH gene mutational status and other prognostic markers.

Neoplasma - 1 Jan 2006

Schwarz J, Mikulenková D, Cermáková M, Polanská V, Michalová K, Marinov I, Campr V, Ransdorfová S, Marková J, Pavlistová L, Brezinová J, Sajdová J, Sponerová D, Volková Z, Benesová K, Cermák J, Vítek A, Cetkovský P

Abstract excerpt

Morphological examination is the routine first step in the diagnosis of hematological malignancies, including chronic lymphocytic leukemia (CLL). Atypical cell morphology according to the FAB criteria is known to herald disease progression. Several years ago, it was proposed that FAB morphology at diagnosis had a considerable prognostic impact. However, this proposal has not been widely adopted in practice. Thus...

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PMID: 16652191

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