Article
Episomal and integrated human papillomavirus in cervical neoplasia shown by non-isotopic in situ hybridisation.
1 Dec 1991
Abstract excerpt
It was postulated that non-isotopic in situ hybridisation (NISH) signal types 1-3 for human papillomavirus in cervical biopsy specimens represent episomal or integrated virus. The aim of this study was to validate this hypothesis by independent molecular techniques. Fresh cervical intraepithelial neoplasia (CIN) and squamous cell cancer (SCC) tissue were examined for NISH signal pattern by hybridising with...
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