Article
Evolution on distributive lattices.
Journal of theoretical biology - 21 Sept 2006
Beerenwinkel Niko, Eriksson Nicholas, Sturmfels Bernd
Abstract excerpt
We consider the directed evolution of a population after an intervention that has significantly altered the underlying fitness landscape. We model the space of genotypes as a distributive lattice; the fitness landscape is a real-valued function on that lattice. The risk of escape from intervention, i.e., the probability that the population develops an escape mutant before extinction, is encoded in the risk...
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