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Article

Localization of candidate regions for a novel gene for Kartagener syndrome.

European journal of human genetics : EJHG - 1 Jul 2006

Gutierrez-Roelens Ilse, Sluysmans Thierry, Jorissen Mark, Amyere Mustapha, Vikkula Miikka

Abstract excerpt

Asymmetric positioning of internal organs is a characteristics of vertebrates. The normal left-right anatomic positioning, situs solitus, sometimes does not occur normaly, leading to laterality defects. Studies in animal models have shown that laterality decisions are mediated by a cascade of genes that lead to the asymmetric expression of Nodal, LEFTA, LEFTB and PITX2 in the lateral plate mesoderm. A search for...

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Identifiers

PMID: 16639409
DOI: 10.1038/sj.ejhg.5201631

Genes

PITX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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