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Article

A genome-scale assessment of peripheral blood B-cell molecular homeostasis in patients with rheumatoid arthritis

26 Apr 2006

Abstract excerpt

OBJECTIVE: While rheumatoid arthritis (RA) is considered a prototypical autoimmune disease, the specific roles of B-cells in RA pathogenesis is not fully delineated. METHODS: We performed microarray expression profiling of peripheral blood B-cells from RA patients and controls. Data were analysed using differential gene expression analysis and 'gene networking' analysis (characterizing clusters of functionally...

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PMID: 16638801
DOI: 10.1093/rheumatology/kel095

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