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Article

Epigenetic modification of the X chromosome influences susceptibility to polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism - 1 Jul 2006

Hickey T E, Legro R S, Norman R J

Abstract excerpt

CONTEXT: The cause of polycystic ovary syndrome (PCOS) is unknown, although genetic and environmental influences are clearly implicated. Some genetic studies have suggested the involvement of X-linked genes in PCOS, but the influence of X chromosome inactivation (XCI) on manifestation of this disorder has not previously been examined. OBJECTIVE: The objective of the study was to test the null hypothesis that XCI...

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Share to Chromosomes, Human, X
Share to Epigenesis, Genetic
Share to Genes, X-Linked

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16636126
DOI: 10.1210/jc.2006-0069

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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